Welcome to R-DeeP 2.0


R-DeeP 2.0 is a database on RNA-dependent proteins in HeLa S3 and A549 cells resulting from the concept of RNA Dependence and its experimental conversion











References
R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. Caudron-Herger et al. Molecular Cell 2019.
Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP. Caudron-Herger et al. Nature Protocols 2020.
RBP2GO: A comprehensive, pan-species database on RNA-binding proteins, their interactions and functions. Caudron-Herger et al. Nucleic Acids Research 2021.





R-DeeP proteins

4765

HeLa S3 cells

Human Protein of Interest

Enter a protein ID, gene name or protein name into the search field:

Search Result





R-DeeP proteins

3743

A549 cells

Human Protein of Interest

Enter a protein ID, gene name or protein name into the search field:

Search Result





Help and Documentation


  • R-DeeP 2.0 is a database on RNA-dependent proteins in HeLa S3 and A549 cells resulting from the concept of RNA Dependence and its experimental conversion. R-DeeP 2.0 offers two search options, which can be accessed via the sidebar under Single search and Advanced search.

  • The Single search option can be used to search the database for single proteins in HeLa S3 and A549 cells respectively. The button About the Format gives more details about the available input formats that can be used to search for a protein of interest.

  • The Advanced search offers the possibility to search simultaneously for a list of proteins in both HeLa S3 and A549 cells. The result of the search indicates already for each protein whether data is available or not, and whether the protein is presenting an RNA-dependent shift or not.

  • The search results can be downloaded depending on the content as CSV, PDF or HMTL files for archiving or further data processing and analysis.

  • The References menu offers a selection of helpful links to proteins-related databases, protein-protein interactions databases, and RNA-binding-related databases and publications

  • Information on how to cite and related publications and databases can be found under the About section from the sidebar menu.

  • The sidebar is dynamic and can be removed by clicking on the list icon next to the R-Deep 2.0 logo at the top left corner of the screen.



A detailed and user-friendly documentation can be downloaded here:



References and Links

About R-DeeP 2.0

How to cite

Published: 12 December 2022

Rajagopal et al., Proteome-Wide Identification of RNA-Dependent Proteins in Lung Cancer Cells, Cancers, 2022


Related publications

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. Caudron-Herger et al. Molecular Cell 2019.

Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP. Caudron-Herger et al. Nature Protocols 2020.

RBP2GO: A comprehensive, pan-species database on RNA-binding proteins, their interactions and functions. Caudron-Herger et al. Nucleic Acids Research 2021.


Related databases


Contact

The authors of the R-DeeP 2.0 database can be contacted at the following email address

databases.diederichslab(at)dkfz.de